Slicker than a Harlem shakedown, Across 110th Street "hits hard" (Cue) with a jacked-up, smacked-down thrill-ride through the hell-raisin' hoods of Harlem! Cooler-than-cool Anthony Quinn leads a hot cast, including Anthony Franciosa and Yaphet Kotto, in a "hair-raising" (Motion Picture Herald) cop thriller that packs a double barrel of "gory vengeance raw, ugly and unnervingly real" (Playboy)! When a crew of gun-totin' gangstas knocks over a Mafia racket in Harlem, their plan gets blown to hell and the crib gets blown to bits! But as the bullets start flyin' and cops start dyin', a pair of New York's finest (Quinn and Kotto) are forced to work together to bring justice to the streets before the Mafia brings the ghetto to its knees! Now, wanted by the Man and hunted by the Mob, there ain't no way these homicidal homeboys are getting across 110th Street exceptin a body bag!